Peer-Reviewed Journal Articles

Gulfam M, Sahle FF and Lowe TL. Designing Strategies for Chemical-Responsive Programmable Nanotherapeutics (Invited). Drug Discovery Today 24(1): 129-147, 2019. DOI: 10.1016/j.drudis.2018.09.019.

Sahle FF, Gulfam M and Lowe TL. Designing Strategies for Physical-Responsive Programmable Nanotherapeutics (Invited). Drug Discovery Today 23(5): 992-1006, 2018. DOI: 10.1016/j.drudis.2018.04.003.

Kim YS, Gulfam M and Lowe TL. Thermoresponsive-co-Biodegradable Linear-Dendritic Nanoparticles for Sustained Release of Nerve Growth Factor to Promote Neurite Outgrowth. Molecular Pharmaceutics 15 (4), 1467–1475, 2018. DOI: 10.1021/acs.molpharmaceut.7b01044.

Janagam DR, Ananthula, S, Chaudhry K, Wu LF, Mandrell TD, Johnson JR and Lowe TL. Injectable In Situ Forming Depot Systems for Long-Acting Contraception. Advanced Biosystems Available online August 25, 2017. DOI: 10.1002/adbi.201700097.

Janagam DR, Wu LF and Lowe TL. Nanoparticles for Drug Delivery to the Anterior Segment of the Eye. Advanced Drug Delivery Reviews Editor’s Collection Issue. 122: 31-64, 2017. DOI: 10.1016/j.addr.2017.04.001.

Janagam DR, Wang LZ, Ananthula, S, Johnson JR and Lowe TL. An Accelerated Release Study to Evaluate Long-acting Contraceptive Levonorgestrel-containing In Situ Forming Depot Systems. Pharmaceutics 8(3):28, 2016.

Imai H, Misra GP, Wu LF, Janagam DR, Gardner TW and Lowe TL. Subconjunctivally Implanted Hydrogels for Sustained Insulin Release to Reduce Retinal Cell Apoptosis in Diabetic Rats. Investigative Ophthalmology & Visual Science 56: 7839-7846, 2015. Feature Research in the “EURETINA-Brief” of the European Association of Retina Specialists in 2015.

Kotanen CN, Janagam DR, Idziak R, Rhym L, Sullivan RJ, Wilson AM, Lowe TL and Guiseppi-Elie A. Partitioning of Coomassie Brilliant Blue into DMAEMA containing poly(HEMA)-based Hydrogels. European Polymer Journal 72: 438-450, 2015.

Ananthula, S, Janagam DR, Jamalapurama S, Johnson JR, Mandrell TD and Lowe TL. Development and Validation of Sensitive LC/MS/MS Method for Quantitative Bioanalysis of Levonorgestrel in Rat Plasma and Application to Pharmacokinetics Study. Journal of Chromatography B 1003:47–53, 2015.

Misra GP, Janagam DR and Lowe TL. Effect of Excipients on the Stability of Insulin Lispro. Macromolecular Symposia 351(1):46-50, 2015.

Wu LF, Janagam DR, Mandrell TD, Johnson JR and Lowe TL. Long-Acting Injectable Hormonal Dosage Forms for Contraception. Pharmaceutical Research 32(7):2180-2191, 2015.

Wu LF, Li XX, Janagam DR and Lowe TL. Overcoming the Blood-Brain Barrier in Chemotherapy Treatment of Pediatric Brain Tumors. Pharmaceutical Research 31(3):531-540, 2014.

Gil ES, Wu LF, Xu LC and Lowe TL. β-Cyclodextrin-poly(β-Amino Ester) Nanoparticles for Sustained Drug Delivery across the Blood-Brain Barrier. Biomacromolecules 13(11):3533-41, 2012.

Huang X, Wu LF, Li XX and Lowe TL. Thermoresponsive and Biodegradable Hydrogels for Sustained Release of Nerve Growth Factor to Stimulate Neurite Outgrowth. Macromolecular Symposia 317-318: 301–309, 2012.

Yuan W, Li G, Gil ES, Lowe TL and Fu BM. Effect of surface charge of immortalized mouse cerebral endothelial cell monolayer on transport of charged solutes. Annals of Biomedical Engineering 38(4):1463-72, 2010. PMID: 20087768.

Misra GP, Singh RS, Aleman TS, Jacobson SG, Gardner TW, and Lowe TL. Subconjunctivally Implantable Hydrogels with Degradable and Thermoresponsive Properties for Sustained Release of Insulin to the Retina. Biomaterials 30(33):6541-6547, 2009. PMID: 19709741. NIHMS138962.

Gil ES, Li JS, Xiao HN and Lowe TL. Quaternary Ammonium β-Cyclodextrin Nanoparticles for Enhancing Doxorubicin Permeability across the in vitro Blood Brain Barrier. Biomacromolecules 10(3): 505-516, 2009. PMID: 19216528.

Huang X, Misra GP, Vaish A, Flanagan JM, Sutermaster B and Lowe TL. Novel Nanogels with Both Thermoresponsive and Hydrolytically Degradable Properties. Macromolecules 41 (22): 8339-8345, 2008.

Stover TC, Kim YS, Lowe TL and Kester M. Thermoresponsive and Biodegradable Linear-Dendritic Nanoparticles for Targeted and Sustained Release of a Pro-apoptotic Drug. Biomaterials 29 (3): 359-369, 2008. PMID: 17964645.

Huang X, Zhang Y, Donahue HJ and Lowe TL. Porous Thermoresponsive-co-Biodegradable Hydrogels as Tissue Engineering Scaffold for 3-D in Vitro Culture of Chondrocytes. Tissue Engineering 13 (11): 2645-2652, 2007. PMID: 17683245.

Kim YS, Gil ES and Lowe TL. Synthesis and Characterization of Thermoresponsive-co-Biodegradable Linear-Dendritic Copolymer. Macromolecules 39 (23): 7805-7811, 2006.

Li JS, Xiao HN, Kim YS and Lowe TL. Synthesis of water-soluble cationic polymers with star-like structure based on cyclodextrin core via ATRP. Journal of Polymer Science Part A: Polymer Chemistry 43 (24): 6345-6354, 2005.

Huang X and Lowe TL. Biodegradable Thermoresponsive Hydrogels for Aqueous Encapsulation and Controlled Release of Hydrophilic Model Drugs. Biomacromolecules 6(4): 2131-2139, 2005. PMID: 16004455. One of the Top Read Articles of the Season.

Kim YS, Lim JY, Donahue HJ and Lowe TL. Thermoresponsive Terpolymeric Films Applicable for Osteoblastic Cell Growth and Noninvasive Cell Sheet Harvesting. Tissue Engineering 11(1-2): 30-40, 2005. PMID: 15738659.

Huang X, Nayak BR and Lowe TL. Synthesis and Characterization of Novel Thermoresponsive-co-Biodegradable Hydrogels Composed of N-isopropylacrylamide, Poly(l-lactic acid), and Dextran. Journal of Polymer Science Part A: Polymer Chemistry 42: 5054-5066, 2004.

Lowe TL, Strzelec A, Kiessling LL and Murphy RM. Structure-Function Relationships for Inhibitors of beta-Amyloid Toxicity Containing the Recognition Sequence KLVFF. Biochemistry 40: 7882-7889, 2001. PMID: 11425316.

Lowe TL, Virtanen J and Tenhu H. Hydrophobically Modified Responsive Polyelectrolytes. Langmuir 15: 4259-4265, 1999.

Lowe TL, Tenhu H. and Tylli H. The Effect of the Hydrophobicity of a Drug on Its Release from Hydrogels with Different Topological Structures. Journal of Applied Polymer Science 73: 1031-1039, 1999.

Lowe TL, Virtanen J and Tenhu H. Interactions of Drugs and Spin Probes with Hydrophobically Modified Polyelectrolyte Hydrogels Based on N-Isopropylacrylamide. Polymer 40: 2595-2603, 1999.

Lowe TL, Benhaddou M and Tenhu H. Thermal and Rheological Properties of Hydrophobically Modified Responsive Gels. Macromolecular Chemistry and Physics 200: 51-57, 1999.

Lowe TL, Benhaddou M. and Tenhu H. Partially Fluorinated Thermally Responsive Latices of Linear and Crosslinked Copolymers. Journal of Polymer Science Part B-Polymer Physics 36: 2141-2152, 1998.

Lowe TL and Tenhu H. Interactions of Thermally Responsive Polyelectrolyte Latices with Low Molar Mass Organic Molecules Studied by Light Scattering. Macromolecules 31: 1590-1594, 1998.

Lu T, Vesterinen E and Tenhu H. Dynamic Light Scattering studies on Polyelectrolytic Derivatives of Poly (N-isoprpylacrylamide). Polymer 39: 641-650, 1998.

Theme Issue Editor

Theme Issue “Nanotechnology Enabled Regenerative Medicine for Neurological Disorders”, Advance Drug Delivery Reviews, 2018. Accepted and In Progress.

Theme Area. Regenerative Engineering and Translational Medicine, 2017. Accepted and In Progress.

Special Issue “Advanced Ocular Drug Delivery”, Pharmaceutics, December, 2017.

Book Chapters

Misra GP, Gardner TW and Lowe TL. Hydrogels for Ocular Posterior Segment Drug Delivery (Invited). In Drug Product Development for the Back of the Eye. Kompella UB and Edelhauser HF, Eds. AAPS Advances in the Pharmaceutical Sciences Series 2: 291-304, 2011. Springer. New York, New York.

Misra GP, Imai H, Singh RSJ, Lowe TL and Gardner TW. Diabetic Retinopathy and Diabetic Macular Edema (Invited), In Retinal Pharmacology. Nguyen QD, Rodgriques EB, Farah ME and Mieler WF, Eds. Elsevier, Pages: 134-137, 2010.

Misra GP, Gil ES and Lowe TL. VI: In the Biomedical Arena. In Grafting and Cross-linking on Polymers: Principals and Applications. Bhattacharya A, Rawlins JW and Ray P, Eds. John Wiley & Sons Inc. Hoboken, New Jersey, Pages: 145-175, 2009.